I'm 56, post-menopause for 6-8 years (my memory sucks) and have been struggling with brutal fatigue, joint pain, brain fog for the last couple of years. I work full time, love my job but have been having to miss a lot, to the point that I was considering applying for disability (I have Sjogren's Syndrome and thought that was the main issue). I've tried so many different things, seen so many different doctors, and none of them suggested HRT (?!)
It took me having abdominal pain and vaginal atrophy to get me in with a new gyn, and I had already decided after doing a lot of reading that I needed to try HRT. I had a DVT 22 years ago due to a perfect storm of risk factors occurring all at once (pregnancy, bed rest, obesity, abdominal surgery, left in bed after surgery for days with no compression on my legs cuz they didn't do that back then.) And due to that, I'd been told early on that estrogen was a no go. I finally decided to push back against this since the DVT happened in a really extreme circumstance and I haven't had one since and don't have any of the risk factors now.
Dr finally agreed with me, and I was excited to get prescriptions for progesterone pills, Estradiol cream, estrogen patch, and even testosterone (though apparently they have to compound it at a special pharmacy? I'm picking it up today.)
I've been using the estrogen cream vaginally for two weeks, the progesterone for about a week, applied my first patch last night and will start the testosterone as soon as I pick it up.
Issues so far, the vaginal cream is goopy and leaks out for days so I'm having to wear a pad daily. Hoping that gets less-so now that I can drop down to twice a week. No other real problems with that and I do think it is already helping with the vaginal atrophy.
The progesterone was hard. Tried taking it before bed and it knocked me out within 20 minutes but I felt awful in the morning, exhausted and drugged, and had to go try to make it through work. Paused it a few days then started it again when I had 4 days off and by the time I had to go back to work, it wasn't as bad.
Started the estrogen patch last night and was nervous but slept well. Felt awful in the morning, though - exhausted and sore all over, had to call in to work and am in bed, resting and taking Tylenol 750. I know the first few days, weeks can be hard but I'm really hoping to feel better by Monday, at least enough to make it to work. Maybe the testosterone will help.
Trying to be positive, because this is my last resort to try to keep working and keep my job. Can I ask what others have found the first few weeks on the estrogen patch and how long it took to start seeing benefits?