Runtime 1:45:52. Minor edits from the theatrical/physical media version that removes some nudity and violence.

Inspired by the popular French comic book of the same name.

Interestingly writer/director Jan Kounen partook in an ayahuasca ceremony in Peru under the auspice of research and later coaxed lead actor Vincent Cassel into traveling and doing a ceremony as well. Jan cast the actual Peruvian shaman to play the role of the elder shaman in the movie.

Cast includes Vincent Cassel, Michael Madsen, Juliette Lewis, Temuera Morrison, Ernest Borgnine, Eddie Izzard, and Djimon Hounsou.