Sean McVay just loves pounding the run against the Cardinals. Rams rushing yards in the last 6 games against ARZ (or last 3 years): 143, 249, 68, 53, 228, 179. This comes out to an average of 153 yards. The two games in 2024, the offense was held in check for 13 and 10 points. Basically, as long as the Rams offense isn't stifled and is able to meet their projections, both RBs should be able to hit 70+ yards with good TD equity.

Edit:
Blake Corum has 2TDs in 2 games against the Cardinals
Kyren Williams has 6TDs in 6 games against the Cardinals