I have been TTC for 3 years officially and unofficially like 6, my husband and I never used protection. We have 3 losses under our belts the most recent last week.

My best friend knows this and has a 9 month old and is in her second trimester with her second and shes been constantly complaining about her child and pregnancy. And I've been there for her but I'm just at a point right now where I cant.

She knows about the recent loss, I did gently tell her I mentally cant handle the venting right now and i a pretty sure she forgot.

I'm not like extremely mad at her and shes not a horrible person I'm just frustrated and really sad especially tracking this cycle to make sure the Letrozol worked and I get my period even if its later than usual. It also doesnt help that theres 3 women pregnant in my church and one of them was a few weeks ahead of me and I'm just.. not expecting my baby on mother day anymore and kinda wanna sleep and not wake up again.

Caveat: I am slightly depressed but won't ever do anything I love my husband and my life, I have a great support system so please dont read into the sleeping forever thing. Its just how I feel right now.

Just a vent, I guess but always would love to hear other people success stories and vents as well.
My insurance doesn’t cover anything fertility, including letrazole.
My husband and I both agreed to wait at least another year and a half before committing to spending thousands on treatment.
I do ovulate 3-6 times a year (usually 4) and the lack of chances we get is devastating me.
I’m now on month 4 with only one ovulation, we timed everything perfect and still a no go.
Yet everyone around me is becoming a mom, even though I’m the one who has wanted this the most/longest.
I’m ready for my announcement, but I’m sure even when the day comes, I’m so traumatized by this process that I won’t be able to be truly happy until my baby is actually here.

My last cycle was the first time tracking, I had a classic cycle with cervical mucus(that I only checked the day after ovulation so I couldn’t know for sure) and a positive LH strip, and a good progesterone blood test a week later.

I get between 3 to 6 periods a year.

I have had egg white cervical mucus for the last six days, most notably the last three days I have found a lot. However, my LH is still nowhere near ovulating.

When I got my estrogen test tested, it came back completely normal a few months ago.

How long do you see cervical mucus before you ovulate

Hey, im new to the group, ill preface this by saying I dont have PCOS, my wife does and her and i are currently trying to conceive. We are working with Shady Grove Fertility in Eastern Pennsylvania, we love them so far but they are recommending timed intercourse with Letrozole and a trigger but the price per round is a thousand dollars which we don't have. We are looking into just seeing if she can do letrozole and no trigger as the biggest barrier with conception at this time is the lack of ovulation. Any advice and thought are greatly appreciated thank you!

I'm really struggling with whether trying to argue with my fertility team about AH is worth it. I'm 27 (turning 28 in a few weeks) and am hoping to undergo my first round of FET soon. I went through 6 failed rounds of IUI.

My issue is that I received my treatment plan and assisted hatching is on it but I don't see it as necessary at the current time. I've done the research and read multiple studies and reports that indicate that there is no sufficient evidence on the performance of AH. Additionally, my insurance did deny coverage of AH because of this lack of evidence so I would be covering it out of pocket. Affording it isn't the issue but the out-of-pocket cost did play a factor in my research and decision.

With this being my first FET and my age, I don't believe its necessary but my clinic is being very insistent about it. I have 15 embryos and am willing to take the risk of failure.

The advice I need is, should I just give in and go along with the AH? What has been your experience with AH? Did you chose not to do AH and later regret that choice?

I started Ovasitol in July for high testosterone. I just got it rechecked and it had dropped to 44 from 65. I used Provera in September to induce a period and now currently cycle day 27 with no signs of ovulation. I’ve been on Ovasitol for 3 months. Should I continue? Add metformin? I’m just shocked I haven’t ovulated by now. Any advice?

I just started 400mg of progesterone 4 days ago where I was at 200 previously but I never got my period after I finished it this last time. I’m now bleeding, not just spotting, and I still have the 6 days left to take it. Did this happen with anyone else to bleed like a period in the middle of the progesterone cycle?

I recently had my HSG procedure done and the fertility clinic is recommending a follow up fluid ultrasound due to a potential (small) fibroid or polyp. Has anyone experienced this? My insurance doesn’t cover any fertility services and everything is so expensive. I sometimes wonder if these recommendations are money grabs…

This is my first time trying letrozole. I took it 2.5mg days 3-7 on my cycle and had some nausea, headache and irritability but other then felt fine. Now I’m cycle day 11, 4 days after my last dose and I’m having the worst time. I feel dizzy like I’m spinning, nausea, anxiety and mild cramps and bloating. Has anymore else experienced this?

Hello everyone,

My provider prescribed letrozole -3 pills 2.5mg (7.5mg total) for CD3 and 4. I haven’t really seen anyone talk about that course of letrozole anyone has a similar experience ?

This is my first time TTC. My husband and I have been trying for about 4 months, and I am starting to get discouraged. All of my doctors are saying "loose weight and stop stressing", but the stress part is almost impossible... In hopes to help with my insulin resistance, the doctors prescribe wegovy the pill and metformin. I haven't been formally diagnosed with PCOS, but have the insulin resistance.. My BMI is 33. I am only 23 and this is so mentally exhausting. Has anyone had anything similar? Any success? Any other advice? I am open to any an all...

I’m already on 1500 metformin , nac,40:1 inositol, fish oil , coq10, prenatals, vitamin d.. anything I’m missing here other then losing weight ( I’m trying 😭)

Has anyone gotten pregnant while on 5mg of triz with letrozole?

Hi all,

My husband and I are currently in the waiting phase of our second round of fertility cycle. We are doing TI with letrozol, trigger injection, and progesterone.

I am scheduled to go for my labs on Friday to confirm if pregnancy was successful, but I already know it my heart that it wasn’t. I took a pregnancy test today and it was negative.

I am so angry and sad because I thought with the hormones this would be the round! My follicles looked good and I was ovulating, so what happened?!?

We have one more round to try before we have to try other method options, but this has been so much harder than I expected.

In the time since our last failed cycle, a close friend and cousin have announced their pregnancies.

I’m defeated at this point.

Thank you for letting me share this with people who understand exactly what I’m going through.

Hi All,

Sorry for the long post (rant)

I (32F) had my IUD removed in February of this year. I had had IUD coverage with no periods for a blissful 10 years and i maybe naively thought i would start ovulating soon after it was removed.

For the first 10 weeks i didn’t ovulate and didn’t bleed. I then had a couple of 35 day ‘cycles’ which were anovulatory as i was testing daily with LH strips (ADHD obsession with needing to know) and the bleeding was more heavy spotting than a ‘period’.

I then started heavy spotting and it was constant for 12 weeks. I was lucky enough to see a really good GP who referred me for an ultrasound scan and i started a progesterone challenge (i was iron deficient at that point). I also had PCOS bloods taken and they were all bog standard normal.

The progesterone challenge seems to have worked and i’ve had super heavy and painful withdrawal bleeds. But due to the progesterone we haven’t been actively TTC.

I had my USS at the weekend and it showed i had Polycystic ovaries, with the smaller ovary measuring 10.4 in volume but she said the other was significantly raised. I had extremely erratic periods as a teenager but started BC fairly early so it was never investigated. I did have an USS when i was about 26 which showed the same and my GP at the time told me to start TTC (helpful when i was single) but due to the IUD they couldn’t diagnose me formally, so it wasn’t a shock.

My question is: I honestly don’t know how you TTC in situations like mine, i feel like all of the joy and excitement of TTC has been robbed by my own body. I’m already taking Myo-inositol and Dchiro (40:1) and i will start actively trying to be more active and eat healthily, but how am i supposed to know if i’m ovulating, do i need to test daily? I’d like to at least try to conceive naturally before inducing ovulation.

Again, Sorry for the long post. I would be grateful for any ideas/shared experiences.

Thanks for reading ☺️

So I (26f) and husband (27m) had really high hopes for this first letrozole cycle, but I didn't ovulate. I stopped testing around CD 25 since I saw no rise, and will be starting progesterone to kick start another cycle. Did any of you have success with the 5mg after a failed 2.5mg? Really needing something to keep me going ❤️

So me and my husband (both 29) have been trying since December 2025. To make a long story short I either wouldn’t ovulate and have a 40-50 day cycle or I had three months total where I would get a positive LH test but it was between 24-27 of my cycle and a shortish luteal phase (9-11 days). For context I have always had 35 day cycles since I was a teenager with an occasional super long cycle usually around stress. We were able to get with a fertility doc in July and confirmed I had PCOS. Luckily my husband’s numbers are above average so we aren’t dealing with any male factor issues.

A concern was my prolactin was in the 50s and through medication I have now gotten it down to a 15 which is well within normal range. We just finished our second cycle of Letrozol, trigger shot, timed intercourse, and progesterone supplement with no luck.

My doctor said we can do the timed cycle up to 6 tries but really if it’s going to work it will work within 3-4 tries. My husband and I are open to IVF, and luckily through my work I have fertility benefits so if we were to do it cost would not be a factor in our decision making. My doctor asked if we would be interested in doing one more letrozol round and then an egg retrieval in November since we have already hit our deductible this year. Then we can take a break in December and depending on how well that goes we can determine next steps from there.

Idk why I feel hesitant to already jump to IVF? For some reason I feel like it’s cheating because we haven’t tried for a year but I feel like if I tried for 3 more months with no luck I’d regret not having gone ahead with it. I know IVF is not easy don’t get me wrong! I’m lucky that my husband is comfortable giving shots (he has some medical experience in his past) and has committed to giving me all my shots and tracking the meds. We also want a big family (like 3-4 kids) so this could also make that more of a reality if we can preserve my fertility now. Also my doctor and I spoke about the supplements I’m on (inositol, prenatal, COQ10, etc.) and she doesn’t think we need to add anything else based on how long I’ve taken those for better egg retrieval success.

I guess if you were in my position is there any reason you can think of to wait to do an egg retrieval or IVF?

This might be a long story but i’ll try my hardest to make it short. I’ve been on birth control (pill) since i was 15 and i’m now 24. i only had 2 periods when i first got it and they were super heavy…then they just disappeared. Looking back at my records they had suspected PCOS but nothing else was done. (my grandma raised me so the way of teaching and hush hush of the reproductive system was something not talked about to me) Just recently in July i stopped BC. i honestly feel like a new person and my mood is amazing. I had 2 periods (only ovulated once) and now they are non existent. I have now officially been diagnosed with PCOS for 3 years now. My OB wants me to wait 6 months before he puts me on any medication. Which yeah i get it but why can’t i get started on something in this 6 month period. i take 1,000mg metformin, prenatals, and maca root. i just get really devastated on why they wouldn’t have started me on something. I didn’t want to be rude to the OB but idk if this is something normal where i have to wait or could i talk to someone else?
i saw a meme yesterday saying i would eat a dirty toenail for a positive pregnancy test and it fr is that deep😭

I really want to become a mom, and honestly, I’m starting to feel like my body is failing me. 💔 Nothing I’ve tried so far has worked, and dealing with this every month is emotionally draining and heartbreaking. I have PCOS and irregular periods, and I suspect I may have insulin resistance. I’ve had two HSGs and three vaginal ultrasounds, and most of my test results have come back pretty normal. I also have a pituitary tumor, but I’m not sure if it could be affecting my fertility.
I’ve never been on birth control, but I’m now considering it just to help regulate my periods because I can go months without having one. At the same time, I’m scared of doing anything that might delay my chances of getting pregnant. I’m honestly at the point where I feel like giving up because this journey has taken so much out of me emotionally.
For those who have PCOS or have been through fertility struggles, I have a few questions:
• What tests should I ask my doctor to run to make sure we aren’t missing anything?
• Could insulin resistance be affecting my ovulation, even if most of my labs look normal?
• Could my pituitary tumor be affecting my periods or making it harder to get pregnant?
• Has anyone used metformin or other treatments to help with PCOS and ovulation?
• Is birth control a good option for regulating periods if I want to conceive in the future, or are there better options?
• What kind of doctor should I see next: an endocrinologist, an OB-GYN, or a reproductive endocrinologist?
• Has anyone been in a similar situation and eventually gotten pregnant? What helped you?
I would really appreciate any advice, personal experiences, or suggestions for questions I should bring to my doctor. I’m trying to stay hopeful, but this journey is so much harder than I ever imagined. I just want to be a mom. ❤️‍🩹

I’m 32 years female, trying to conceive, so my doctor has prescribed me metformin and I’m starting from tomorrow 500 MG for a week and I’ll be taking it once a day. After that, will be going for twice a day. I have mild PCOS and irregular periods. I am overweight. I have insulin resistance, pre diabetic. I have started walking every day in the morning for an hour also started with my diet and lifestyle changes. I am trying to conceive for quite some time now and it’s really frustrating at this point, and I’m so anxious and nervous 😭

Would like to hear success stories related to this. I know it’s not a weight loss, but I’m just curious to know if any of you lost some weight and regarding the pregnancy and ovulation, I would like to hear your stories, thank you so much ♥️

Has anyone received an unexplained fertility diagnosis while having PMOS? I have ovulatory pmos and have pretty regular cycles with ovulation typically occurring cd 16. I may have a couple longer cycles per year, but generally speaking my cycles are regular.
I’ve been doing research on possible next steps (not ready to commit to IVF, which was the path encouraged by my RE), but all PMOS related infertility treatments seem to focus on making ovulation happen. There’s very little information out there for people with ovulatory PMOS, aside from diet and lifestyle changes, which I already comply with.
I’ve tried letrozole, even though I naturally ovulate, after reading something about how it can improve egg quality, and no luck after 4 rounds with confirmed ovulation each time. I donated eggs when I was 22 (8 years ago) and the couple successfully delivered, so I don’t think egg quality is the issue (unless there’s been a drastic change).
I’ve been taking inositol and coq10 for over a year. Clear hsg, no issues on hysteroscopy. Weekly acupuncture for 5 months. Everything good on SA except borderline morphology (3.5%). Baby aspirin and prenatals daily. I haven’t seen one positive test after 14 months of trying.
I’m wondering if anyone’s been in a similar situation and what worked for them? I really feel like my PMOS is contributing to my difficulty conceiving, but I’m not sure how.

Hello, I’m just looking for a bit of anecdotal advice a bit what you would do in my situation.

For context, I’ve (30F) had 3 miscarriages in the last year, 1 suspected ectopic (Oct 2025) 1 chemical at 6 weeks (Feb 2026) and 1 MMC (April 2026) which I had removed by D&C at 10 weeks (genetic testing showed it had Turner’s Syndrome)

All of these pregnancies were conceived ‘first try’, and without support. I have PCOS, was diagnosed 4 years ago and through metformin and inositol/diet etc, was finally ovulating by myself.

After lots of recurrent miscarriage related tests, everything came back clear. I decided to use letrozole to try and ‘optimise’ my ovulation, as I was told that a luteal phase defect could have contributed to my miscarriages.

I was on 2.5mg, producing 2 follicles and triggered on CD18. I didn’t think I’d need a trigger, and I thought I’d ovulate a lot earlier (I normally ovulate CD16-18 naturally), so I was quite surprised at my response from it. I did have multiple follicles at 12mm on CD 10 and 12, before the two front runners pulled ahead so I wondered if the reason for the later ovulation was from that. I’ve been on progesterone since CD20.

Anyway, I’ve not conceived this cycle. My conundrum is, do I try another month at 2.5mg? Or do I try again naturally, and see if I can have progesterone support after ovulation?

My clinic was slightly bemused that I wanted letrozole anyway since I ovulate on my own, but I now feel like if I try and have a natural cycle, I might not ovulate or I might miscarry again.

Am I ‘safer’ trying the letrozole again? I know it’s luck of the draw, it’s just such a head spinner when I’ve conceived first try every other time only to miscarry.

What would you do in my situation? I can’t find any strong anecdotal evidence one way or another.

Thank you so much for your help!

I’m currently breastfeeding my baby and trying to conceive again. My cycles aren’t back.
My fertility specialist prescribed Clomid 100mg daily for 5 days. I had my day 13 follicle-tracking scan today, and my largest follicles were around 16mm. My uterine lining was only 3.5mm (it was 2mm before starting Clomid).
My specialist said my response is a bit slow but that the follicles still appear to be growing. He said it could take another week for them to be ready, and suggested we could start trying later this week, although I might not ovulate until the middle of next week.
I’m worried that breastfeeding might be affecting my hormones and preventing my follicles from growing properly. I’m also concerned about my thin uterine lining.
If this cycle doesn’t work, my specialist may consider increasing my Clomid dose.
Has anyone been in a similar situation?
Did your follicles continue growing after day 13 on Clomid 100mg?
Did you ovulate later than expected?
Were you breastfeeding, and did it affect your response to Clomid?
Did your uterine lining improve as your follicles matured?
Did you need a higher dose in a later cycle, or did the 100mg eventually work?
I’d really appreciate hearing about your experiences, particularly from anyone who conceived while still breastfeeding. ❤️