r/wikipedia • u/syanxde • 3h ago
Benzodiazepine withdrawal syndrome (BZD withdrawal) is the cluster of signs and symptoms that may emerge when a person who has been taking benzodiazepines develops a physical dependence on them and then reduces the dose or stops taking them without a safe taper schedule.
Typically, benzodiazepine withdrawal is characterized by sleep disturbance, irritability, increased tension and anxiety, depression, panic attacks, hand tremor, shaking, sweating, difficulty with concentration, confusion and cognitive difficulty, memory problems, dry mouth, nausea and vomiting, diarrhea, loss of appetite and weight loss, burning sensations and pain in the upper spine, palpitations, headache, nightmares, tinnitus, muscular pain and stiffness, depersonalization, restless legs syndrome, seizures, suicidal ideation, and a host of perceptual changes.
Benzodiazepine withdrawal can also lead to disturbances in mental function that persist for several months or years after onset of symptoms (referred to as post-acute-withdrawal syndrome in this form).
Withdrawal symptoms can be managed by educating patients about the nature and expected course of benzodiazepine withdrawal, individualized taper strategies according to withdrawal severity, the addition of alternative strategies such as reassurance, and referral to benzodiazepine withdrawal support groups.