I switched from 300 mgs of Gabapentin three times a day to Pregablin 50 mgs three times a day. I noticed that most of the people taking Pregablin are taking it twice a day. I'm thinking of changing from 50 mgs three times a day to 75 mgs twice a day. I take my 2nd 50 mg dose around 2 pm and get a dip in my mood from 3-5 pm. I'm hoping that I can eliminate this dip in my mood by changing to twice daily dosing. So are there any benefits or downside from switching to twice daily dosing? Thanks.

i recently restarted 50mg lyrica for nerve pain and i haven’t been getting hardly any REM sleep for the past few weeks. i know it’s important for memory consolidation so this scares me. im going both based off my fitbit and the fact that i have used to have multiple very vivid dreams every night and during naps, and always know when im in REM. my fitbit sleep stages have almost always been completely accurate to when im dreaming and i’ve just stopped. it always says REM is too low now. i get them every once in a while but nothing like i used to.

i know im on a low dose but im very sensitive to meds so im not necessarily surprised. my liver breaks some of them down slower according to a genesight test i had done so i need less to have a stronger effect. does anyone have a similar experience or any advice?

50mg twice a day for nerve pain. I have a very unique issue with arthritis between my sternum and clavicle due to missing part of my upper ribs (birth defect). The bone is growing in such a way that it’s now pushing on nerves. I truly felt like my life was over with the nerve pain that had started. I was in a really bad spot. The pain was so bad I was afraid to cough, sneeze, couldn’t lift my arms up.. my life was beyond limited. I have an amazing partner thankfully that’s been there for me thru it all ❤️

I’m feeling like me again and I do have the option to up my dose as needed. For anyone that’s reading this and is experiencing nerve pain and is scared to start on this drug. I hope that you find relief like I did. I do have brain fogginess a little bit, but no more than I did experiencing extreme pain, it’s just different now.

The only other annoying side effect is some dry mouth. Feels like the desert some days. I just keep my water bottle handy haha!

Been taking 300mg of pregab about 3 or 4 times a week for 2 months now. During that timeline, I've had mild to severe panic attacks almost every weekend. Like, I feel an adrenaline rush about to dump and I can't sit still. And then it does rush and I'm in the ER.

Would love any thoughts. Thank you!

Hi all, I started pregabalin in August and have just started experiencing massive amounts of hair fall. I am quite certain it's from pregabalin since nothing else has changed in my lifestyle. I have a doctor's appointment in 2 days to discuss this. I am definitely going to weane off prrgabalin since it has not helped my sciatica pain at all.

Has anyone experienced hair fall and did it stop after you came off pregabalin?

I was prescribed pragiola (pregabaline) when i was 14 in the hospital that i stayed 3 months in. Years later, i took like 5 pills (250g) and it was fun. My biggest mistake. I started taking it more and more. I had a phase when I took it everyday. Im writing this high (i took 1g) if you think about taking it for fun, please dont. I became stupid because of it, i lost 30 kgs, feel like shit when i don’t take it. My liver is ruined, my kidneys too, my life is fucked up. Please don’t.

I tapered off Lyrica and lost 10 pounds so far. Just wanted to share if anyone is trying to stop and wants a little side perk. Everyday seeing the scale drop a little has been motivating. Even if it’s water weight; I look better. Pain is in full effect so we’ll see how long I can hold out.

Dont you need to increase dosage every month becasue of tolerance? And how is it when you stop? Do you feel brutal withdraws?

Just took 300mg twice yesterday, once at 4pm and around 12 am before bed and honestly it’s so good, i feel like i don’t have the thoughts or voice thats in my head that’s there when im anxious or anxiety ridden. I am honestly loving it but ill take it again in a week.

Has anyone on here actually had Pregabalin work successfully to reset a deregulated nervous system or is it just all a load of rubbish and only works to calm nerves while you take it. My phychatrist has prescribed it but I'm reading just about everywhere that once you stop taking it your back to the original problem.

Anyone else experienced Jaw Tension when doubling your dose under Dr supervision?

Hi, I am taking Pregabalin for about 2 years, started from 75mg, now it varies between 150-225mg as initial dose is not doing much anymore. Pregabalin on right dose is giving me motivation, energy, kills anxiety. Unfortunately, after some time this effect weaking hence higher dose.

Knowing that max dose of pregabalin is 600mg/per day I started wondering what do I do when I hit this maximum dose as it'll be only way to maintain the effect. Is it game over and I need to taper, come off from it or what?

My doctor upped my dose to 600mg. I was having some rage and anxiety on 400mg. This has helped so much!

My anxiety and rage are completely gone. I’ve stopped eating emotionally.

It’s a win. :)

I have Bipolar I and OCD, for the record. Anyone in the same position as I was, just know it’ll get better with the right dose.

This drug is a miracle to me. ❤️

Hello all, just wanted to hear some input from other people who take Pregabalin for anxiety and panic attacks, as needed (not everyday).

I have a bit of a tolerance to gabapentin (and therefore Pregabalin as well), as I initially took it everyday and after 2 months started taking it only 2 times a week or so. Cut to about 5 months later, I asked my doctor if we could try Pregabalin because I'm on a glp-1 and with my stomach emptying slower Gabapentin takes 4+ hours to work. My doctor said yes and prescribed me 15 pills of 100 mg of Pregabalin.

My question is how often can I take Pregabalin with it still working for anxiety and panic. I noticed that if I take it too soon to my previous dose, it doesn't really have much of an effect on anxiety. I'm thinking once a week might be the sweet spot for me, but if I have a panic attack I will take it. But for anxiety I think once a week might be my best option.

Would love to hear from people who use this medicine for anxiety and panic as well. Also people who have been taking it for longer, would be interested in your input too.

I have very severe dpdr where I’m almost totally derealised. I no longer experience any body sensation or any internal process/sensation. My nervous system became so wrecked from extreme shock and trauma that I loose sensation daily. I’ve been hospitalized a few months ago and the meds I’ve tried so far have made things a lot worse. An SSRI and mirtazipine in particular. My nervous system is so sensitised now that I experience my body as faint vibrations and sort of broken nerves plus strange functional sensory /neurological symptoms which seem ro get worse and no explanation for. Im terrified. I can’t risk another setback. I just need to hear some honest opinions about this drug so i can make an informed choice whether to try it or not.

Crippling anxiety and ocd that is making me feel like a monster. Will 75mg help my racing thoughts and severe anxiety?

Hello 🙂 After trying several SNRIs and SSRIs without success, my psychiatrist decided to prescribe Clomipramine. I am currently taking 20 mg, and it's impossible for me to go any higher due to highly bothersome side effects. I am feeling a slight improvement. I mainly suffer from anxiety with severe rumination, overthinking, and a continuous need for reassurance. Now, my psychiatrist has prescribed 25 mg of pregabalin (to take in the morning) combined with my 20 mg of Anafranil (in the evening).

I know 25 mg is a very low dose, but I am still hoping for a real effect. I don't experience any sedation with clomipramine, but I am afraid of experiencing it with pregabalin.

Is anyone else taking this clomipramine/pregabalin combination?"

Have a nice day !

Taking 50mg 3 times a day for neuropathy such as electrical, zaps, tingling, and trigeminal pain daily. Does anyone get a headache and actual worse zaps around the two hour mark? Relief lasts for 5 hrs each dose.

I tried for 25 mg and it’s not effective.

If you have any positive stories about being able to discontinue Lyrica at some point for neuropathy, that would be great

I've been on 150mg of Lyrica to treat my Periodic Limb Movements. Last night, on Dr's orders, I doubled the dose and slept 10 hours. All fine and dandy except I am still high as fuck!! Same thing happened initially on 150mg but this is a new level. I'm hoping it passes as my body adapts. As nice as it feels I can't function like this but need it to work. Anyone else experience anything similar?

I’m on 70 mg of pregabalin 2 times a day after about 5-6 hours I get a splitting headache I mean bad like someone is crushing my head it goes away after I take a tablet but is normal ?

I have tried many different medications for many different years, starting on SSRIs about 5 years ago and quitting them on and off. I was prescribed pregabalin 50x3, and it helped with symptoms of my anxiety and physical tension. My psych put me up to 100x3 and the social anxiety benefits that I’m noticing are great. It’s one of the only drugs I’ve found that really genuinely does help me be myself more and talk to people and date better. I am sometimes debilitated by OCD, PTSD, and Panic and pregabalin is one of the only things that has helped me be less in my head and less tense. It seriously is a life saver. I’m going to talk to my psychiatrist about going to 150x3 a day and stop there.

I’m not prescribed pregabalin but I self medicate with it and I was wondering if it has ever been prescribed for ADHD as I feel it alleviates my symptoms more than any stimulant I’ve been prescribed ever has. Does anybody have any experience with Pregabalin and ADHD?

I have read a lot of your guy’s comments and thank you so much for your advice. From what i am seeing most of the problems start happening when you take them 2-3x everyday. If i were to take it once every week would i be able to avoid the problem?

P:S Also appreciate you guys for looking out for me because yes i didn’t exactly get them prescribed but i am aware of the dangers i am getting myself into. I am currently in the worst spot of my life while healing from a shoulder surgery which can take exactly up to a year and i haven’t went out and talked to people, i originally had lots of social anxiety as i started going out it got better but since the surgery my confidence has tanked completely, like i mean plummeted to where i am currently in my head all day. So even if it’s once a week i am willing to keep it to exactly that or even extend the time between every dose.