r/plagueinc • • Sep 06 '26

Cure Mode Let’s assemble the world’s least useful infectious disease team. What useless skill are you bringing to the table?

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358 Upvotes

Edit: This post got way more attention than I thought it would, and I’m having trouble coming up with funny replies on the spot. I’ll try to get to you if I haven’t!

r/plagueinc • • Oct 04 '25

Cure Mode People In Cure Mode.

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882 Upvotes

I've Been Playing Cure Mode On Mega Brutal, Since I Already Beat All Of The Main Game On Mega Brutal, And I Get How Scientists Want To Slam Their Head In The Fucking Wall. "We Want To Go Outside!" MOTHERFUCKER, OVER 100,000 PEOPLE HAVE DIED AND YOU STILL WANT TO TAKE A VACATION?! OH, AND THE PRESIDENT SAID FUCK LOCKDOWN, WELL JUST FUCK ME I GUESS, APPARENTLY THE VIRUS ISN'T THAT IMPORTANT! (This Post Is Mainly A Joke But Also A Way To Get My Anger Out At This World.)

r/plagueinc • • May 04 '26

Cure Mode Luck, or glitch?

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440 Upvotes

I placed my HQ in Greenland, and immediately locked down South America. When I reached there? The infected had already died. Fourteen deaths and a win.

The only Mega-brutal cure ive beaten. 😂

Any explanation would be great!

r/plagueinc • • Dec 24 '24

Cure Mode Oh come on seriously?

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2.3k Upvotes

r/plagueinc • • Jun 01 '26

Cure Mode I am a hero🙏

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173 Upvotes

r/plagueinc • • Jun 13 '26

Cure Mode After 40 reloads I beat the bio weapon on a good instance on mega brutal

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100 Upvotes

I was biting my nails the whole time. Especially because if I failed I had to set things up all over again.

r/plagueinc • • 3d ago

Cure Mode In cure mode, how do I stop people from panicking about dying??

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12 Upvotes

Even when trying to lower the lethality/infection rate, the authority keep collapsing. Any tips?

r/plagueinc • • 29d ago

Cure Mode Finally!

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34 Upvotes

It was really hard but I finally beat all the diseases of the cure mode at mega brutal!

Honestly when you understand how it works it became easier and while I struggle to deal with the prion and the fungus I beat nano-virus, bio weapon and frozen virus at the first try.

r/plagueinc • • Sep 15 '25

Cure Mode I generally hate cure mode for mega brutal

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316 Upvotes

I know it is meant to be the hardest difficulty for the cure mode. However, I feel like the hardest difficulty shouldn't come down to pure luck. Mostly referring to parasite, prion and bio weapon (haven't tried nano virus mega brutal yet). Most mega brutal guides on the wiki can be summed as 'get lucky with pop ups and panic'. You can be going so well but then suddenly something happens and authority drops to 0. For me my authority started to rapidly drop on bacteria when I released the cure. USA got infected due to Olympics on my parasite run. Several prion runs have been ruined due to unlucky events or the prion starts killing. And bio weapon is just 'wait until it starts in South America and pray it hasn't left until you locked it down'.

Also initiatives are completely pointless, all guides I have seen barely touches them since you can spend a lot of money into initiatives just for it to be undone because healthcare started to collapse.

Anyways, thoughts on mega brutal cure mode or just cure mode in general?

r/plagueinc • • 20d ago

Cure Mode Festival of Love

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63 Upvotes

r/plagueinc • • May 28 '26

Cure Mode Bioweapon (Middle East origin) with commentary

47 Upvotes

It's my understanding that bioweapon is a severely misunderstood disease type.

I blame all the terrible guides out there for treating bioweapon as the unbalanced RNG fest it absolutely isn't.

I get so much enjoyment from playing this disease type. It is saddening to hear all discussion of this being around "fear", "torture", or "resetting".

I will try to release more of these as I get motivation (and video making experience).

Bioweapon does vary quite drastically in procedure and difficulty based on origin and discovery date, but most origins are consistently possible.

This run features a Middle East origin bioweapon, the easiest of all the extremely difficult "Tri-Continental Area" origin countries due it to it lacking borders with Russia or Iran. This means that it does not, unlike the rest, actually have a connection to Asia or any non-African air/sea port, which makes it far easier to contain.

I contain the disease with Extreme Measures, connection closings, and prolonged Targeted Quarantine before analysis, then use Infection Control and Contact Tracing to ensure that the disease never escapes confinement until the disease just dies out.

r/plagueinc • • 12d ago

Cure Mode when can i start my shift

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20 Upvotes

r/plagueinc • • May 19 '26

Cure Mode probably felt 1% of pain that the CDC did in 2020

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154 Upvotes

r/plagueinc • • Aug 30 '26

Cure Mode On the edge

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7 Upvotes

Prion at megabrutal, 2 authority left, i was crying thinkin that i had lost when the counter stopped going down ☠️

r/plagueinc • • 3d ago

Cure Mode Well, i tried 😔

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8 Upvotes

r/plagueinc • • Jun 20 '26

Cure Mode Cure mode is driving me absolutely insane

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98 Upvotes

Pictured: Saudi Arabia after the government decided that pandemic control measures are for pussies and every continent just NEEDS the parasite that kills you from diarrhoea. these planes all flew within like a week

i just can't figure out how to effectively play this mode. sometimes i'll start a run and a million people in china and india are already infected, with every person dying of dysentery deciding "yes, now is the perfect time for me to go visit the UK" as soon as i arrive

on runs that don't have DOA starts i'll try to implement lockdowns and politicians will simply respond 'fuck you' within weeks, which of course gives permanent authority reduction too. i'm struggling to figure out how to actually contain the disease when continent-wide measures always piss off the countries that are (for now) uninfected, and a ton of targeted lockdowns would cost more than i can afford. either way the lockdown gets ignored and the shit in figure 1 happens. also yep, i'm investing in the non compliance reducers too. i don't think they care

on top of that i've got infection/fatality reduction and vaccine production to think about too. that's three spinning plates to balance and i can't even afford the containment / noncompliance management one. epidemiologists in real life have my deep sympathy if their job is like this but worse

am i just not cut out for this mode? i got through bacteria fine, and scraped by virus despite it obliterating the entire population of the middle east. i'm just stuck on parasite (AND only on normal difficulty.. oh my god). anyone got any tips for the mode overall? please??

UPDATE: locked in and beat parasite, thought i was doing great and then got my ass handed to me by fungus three times in a row. legitimate nightmare

UPDATE 2: fungus trembles before me. also managed to power through the rest of the disease types up to bioweapon, which i eventually managed to defeat with the minor sacrifice of 3/4 of south america's population. the later disease types were pretty cool but i was definitely having more fun with the earlier ones that had less preposterous transmission patterns, so i'm looking forward to going back to those on harder difficulties. not looking forward to harder bioweapon though </3

r/plagueinc • • May 05 '26

Cure Mode How to quarantine properly in cure mode?

3 Upvotes

Exactly what it says. Someone told me you need to make use of quarantines in cure mode, but idk how to do that properly.

By the way I’m on mobile.

r/plagueinc • • Aug 28 '26

Cure Mode Cure mode Bioweapon origin tier list (mobile)

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18 Upvotes

A while ago, I beat Cure Mode Bioweapon on MB in every origin that isn't banned with China HQ. And now, I ranked every single one of them in terms of difficulty, from hardest to easiest (in my opinion)

The tier list is ordered (the 1st country in any tier is the hardest one of that tier and the last country in any tier is the easiest country of that tier. Example: Turkey is the hardest origin in the Very hard tier, and France is the easiest origin in that tier).

I had a hard time ordering countries in Easy and Free tiers, some of the placements there are debatable. Also, East Africa is arguably harder than Iraq (even though I put Iraq higher)

Afghanistan and Pakistan are missing, they should be in "Banned by China" tier

Also, this tier list is only for a mobile version of the game (Cure Mode is harder on PC)

If you have any questions regarding the placements, fell free to ask them!

r/plagueinc • • Jun 13 '26

Cure Mode guys do you think im finna win

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46 Upvotes

i think i have a good chance🤑🤑🤑🤑🤑🤑🤑

r/plagueinc • • Jul 08 '26

Cure Mode Is mega brutal on cure mode actually possible (mobile)?

8 Upvotes

I've tried every guide I can find and nothing seems to work. Not sure what the deal is, but it seems like mobile is built different.

r/plagueinc • • Aug 12 '26

Cure Mode I saved the world right

12 Upvotes

r/plagueinc • • May 01 '26

Cure Mode How do I get the snow way achievement on mobike if censorship isn’t available?

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107 Upvotes

r/plagueinc • • Apr 03 '26

Cure Mode Cure mode is so bumass

18 Upvotes

I'm just trying to get cure mode on normal for the first time

r/plagueinc • • Jun 03 '26

Cure Mode Argentina Bioweapon (without Expectation Management!)

41 Upvotes

I was meaning to post a bioweapon run that featured a South America origin. Everyone else posted South America, after all....

I also wanted to show that winning Bioweapon in South America doesn't require sacrificing any countries at all!

I call this endgame "Happy Path", as it results in all countries being saved (thereby precluding use of Expectation Management) and minimal authority loss.

This path is also easy to do (when it works), as it only requires Infection Control and Lockdown to close out the game. However, it only works when lockdowns are forced before countries start collapsing, and infectivity growth can sometimes invalidate it.

Here I do exactly that.

Late discovery of the origin resulted in a scramble to mop up infections globally before they could take hold outside of South America. Once this was done with the help of Extreme Measures 2, however, I was able to save Argentina — the origin country — and then progressively save the remaining South American countries until none were left infected.

This was made possible by a relatively early lockdown that delayed Argentina's collapse long enough for Operatives to be able to give their full attention to the country.

All countries were saved, and only 2 authority was lost to panic and deaths.

r/plagueinc • • Aug 10 '26

Cure Mode i saved the world

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31 Upvotes

i’m such a good guy