Hi, I'm here because a I have a gorgeous goofy boy with extremely complex health.
When Mambo was 2 he was diagnosed with idiopathic epilepsy, it took a few years to get the meds right, and those years were really hard. However he's now seizure free for about 2 years now at 6 years old on epipehn and gabapentin.
In 2025 he ate a sausage treat from Asda that gave him the most severe case of pancreatitis many vets had ever seen and we nearly lost him. He was in hospital for about 3 weeks total, 1 at our local emergency and 2 at a specialist when they referred him there because he wasn't getting better. He had a feeding tube, a list of about 15 different meds to get his stomach, pancreas and gall bladder working.
He got better, he came home and continued to get better and we are now out of that terrifying time but we of course have a very strict low fat diet now.
When we got him home after the pancreatitis we moved him from his butchers wet food to royal canin low GI low fat kibble.
A couple of weeks after getting him home he started getting sore skin- he would always get seasonal allergies around late summer and get itchy eyes but it was easily managed and short lived.
At first I thought it was the food, we tried loads of elimination diet stuff all while his skin just kept getting worse, the issue is any specialised diet had to be low fat for his pancreas and not have anything that isn't seizure friendly in too.
He had antibiotics and preds for a while because it got so bad he was outright mauling and goring himself, he would bleed, wounds stayed wet and yeasty, it would clear up and then happen again when he re-injures himself (also preds is not great for a dog with seizures so a massive risk but we had no other option, we started really low but this was nerve-wracking as he was very anxious on it when he first started). We were in hell, he had to be in a cone at night and was miserable and couldn't sleep with it on, we had socks, surgery suits, inflatable cones (didn't work because he has such a long snoot), we tried EVERYTHING.
There was a relatively new brand of hypoallergenic food with hydrolysed protein branded as low fat that had JUST low enough fat we could try him on it, this was the last diet change we could do and the vet agreed he needed to go on cytopoint and that it would be the safest allergy med for him with regards to his epilepsy and pancreas, we would have him on this food for 8 weeks while starting cytopoint and then tested elongating the distance between jabs once he had been on the food this long to see if it had helped, it sadly didn't. We tried to book his next jab a week later than we usually did after this trial and he immediately got an ear infection and itching issues creeping back in. We put him back on royal canin low fat and continued with cytopoint as it was working. He was a happy dog again, almost completely back to normal.
He's been on cytopoint for just under a year now and at the end of the last jab cycle he started itching again and did some damage to his paws, this was thought to be an overwhelm because of allergy season, he had his next jab and seemed ok again, paws healed.
A week and a half into the new jab cycle and it happened again and now I'm terrified because what if cytopoint isn't working anymore? We cannot go back to how it was I cried every day and so did he, we were all miserable.
Because of his complex health I'm seriously terrified of trying apoquel or newer drugs like zenrilia.
Going back to his pancreatitis episode for a moment to explain finances.
He has a lifetime policy with napo, he had that in place a year before he even had his first seizure so everything went onto his insurance, then every renewal his insurance would triple.
When we were in 2025 and he had his pancreatitis he rinsed through all 12g of his insurance getting better, and then some.
We had to continue paying his monthly premium (of 160 GBP) even though his insurance wasnt useable on top of paying for his appts, blood tests, epi meds and now cytopoint injections.
When we got his renewal in it had gone from 160 to 450 per month. Because of the sheer cost of his medication and the necessity of having emergency funds for him we decided to renew but this will be the last year he has on insurance, this renews every may so we are already halfway through.
My thinking is that if he needs more specialist care to get control over his allergies, a referral now is our last hope but it's a risk as you can't be 100 percent sure the insurer will cover a specialist referral.
We are running out of options, right now I have a course of antibiotics for his current skin infection, a spot gel and some antibacterial wipes for when he comes in the door.
It would be great if this was an overwhelm that we can grain control over again and then cytopoint can carry on doing it's job, but I can't help but worry about what to try next if cytopoint is truly not responding for him anymore as I know this can happen.
I hear lots about zenrilia but it's largely the same as apoquel and I'm so terrified of putting my already chronically ill dog on an immunosuppressant.
Since we got Mambo, my health also declined, I can't work and I can't walk anymore either it's a whole other long and complex story but this means that funds are low.
Even though it broke my heart I even looked into rehoming him early this year with the rescue I got him from and previously worked for but honestly, no one is going to take a dog that needs this much money. Having him put down because of money issues is NOT an option because he has so much potential to be a healthy happy boy despite the way the world has downtrodden him. Just like me. This dog has my entire heart, he is everything to me, so I'm desperate to find answers.
Has anyone been through similar and has any advice??
What meds worked for you?
I will be cross posting in canine allergy and canine epilepsy.
Thank you for reading, love Lola and Mambo x