So back in early June, Bryan posted about an n-of-1 study from Brazil involving a woman in her eighties who was administered a 5 g dose of psilocybin-containing mushrooms, specifically the Enigma strain. She had been nonverbal due to Alzheimer's for 10 years, and after the 19-hour trip and sleep, she woke up and spoke for hours about her life.
We've been dealing with a man in the family, born in 1952, who has early-stage Alzheimer's and has begun forgetting names, including those of his daughter and grandchild, but nothing to the extent of the person in the study. In our case, the man's wife did not want to wait for things to get worse and wanted to give this a shot.
Last Tuesday, he was given 3.5 g of dried psilocybin mushrooms, specifically the Penis Envy strain, at around 10:30 am at his house. His room was made as dark as possible, he lay down in bed, and his eyes were covered. He got up once with assistance to use the washroom, then went back to bed with his eyes covered. Eventually, around 3:30 pm, he got out of bed and was fairly euphoric. Nothing extreme, but it called into question whether we should have used a strain with less of a euphoric effect. Eventually, it fully wore off, and he went to bed normally that night.
The results are clearly anecdotal, but positive. His wife and daughter both see a positive shift so far, starting with the man remembering who his daughter is. Six days later, he has more energy to tackle the day-to-day challenges of life and is discovering new things to do, like gardening and cleaning the garage, etc. without being asked.
The plan right now is to do a follow-up dose six weeks later, as they did in the study, this time using the Enigma strain.