r/DogAdvice • u/ravensmama • 6h ago
Advice 9 year old dog, just diagnosed with high grade splenic stromal sarcoma
9-year-old dog diagnosed with a grade 3 sarcoma after her 3rd abdominal surgery. Looking for experiences with treatment and outcomes.
Raven: almost 9, spayed female Lab/shepherd mix, ~ 70 lbs
History
June 2025: A 13 cm mass on her spleen plus enlarged lymph nodes. She had a splenectomy, and pathology came back benign (a hematoma).
April 2026: An 8 cm mass grew where her spleen used to be. The first pathology read suggested lymphoma, but further testing (immunohistochemistry and PCR) ruled that out. The final diagnosis was a benign, reactive lymph node. She also has a ~3 cm right adrenal mass we're monitoring, which has stayed fairly stable.
October 2026: Ultrasound showed two new masses in the same area. Both were removed on Oct 12. A suspected liver mass seen on ultrasound wasn't found during surgery. Chest X-rays before surgery were clear.
Biopsy results (reviewed by 3 board-certified pathologists)
Larger mass: high-grade (grade 3) sarcoma, likely a splenic stromal sarcoma. They believe it grew from leftover spleen tissue (ectopic spleen) left behind after the splenectomy.
Mitotic count over 20: a measure of how fast the cells are dividing, which makes it fast-growing.
Smaller mass: benign nodular hyperplasia, also in leftover spleen tissue.
Margins were clean on both: the masses were fully removed.
Plan: Her surgeon and his oncology colleague are both recommend chemo. We have an oncology consult coming up.
Questions
Has anyone dealt with splenic stromal sarcoma, or a sarcoma growing from leftover spleen tissue? How did your dog do?
For a high-grade sarcoma that was fully removed with no visible spread, did you do chemo (IV doxorubicin or low-dose oral)? How did your dog tolerate it, and did it seem to help?
Did your vet recommend a CT scan for staging beyond chest X-rays?
Has anyone used turkey tail or other supplements alongside chemo?
picture of raven for flare